Cagrilintide raw materials

Cagrilintide Raw Materials

Cagrilintide is a long-acting amylin analogue that achieves a half-life of up to 7 days by replacing multiple amino acids in natural amylin and undergoing fatty acid modification. As a core component of the CagriSema (Cagrilintide + Semaglutide) combination therapy, it holds significant research value in the field of metabolic research.

Key Bioactivities

• Selective activation of amylin receptors: Selectively acts on amylin receptors (AMY1-3), inhibiting post-meal glucagon secretion, delaying gastric emptying, and inducing satiety, suitable for research related to feeding regulation mechanisms.
• Outstanding potential for weight management: Clinical studies show that Cagrilintide monotherapy can achieve significant weight loss. When combined with Semaglutide (CagriSema), the weight loss effect is further enhanced, making it a popular combination research tool in the field of obesity research.
• Improved glycemic homeostasis: Inhibits post-meal glucagon peaks and reduces blood glucose fluctuations, demonstrating excellent results in studies related to blood glucose control.
• Central satiety regulation: Reduces food intake and prolongs satiety duration through amylin receptor signaling pathways in the hypothalamus and brainstem, suitable for neurobiological research of feeding behavior.
• Long-acting structural advantages: Fatty acid modification enables albumin binding, with a half-life of approximately 7 days, suitable for research designs involving once-weekly dosing, significantly superior to natural amylin (half-life of only a few minutes).
• Improved lipid metabolism: Animal studies show it can improve lipid indicators, reducing triglyceride and cholesterol levels, making it a potential tool molecule for lipid metabolism-related research.

Product Features

• Research-grade purity, high batch-to-batch consistency.
• Suitable for in vitro experiments, animal models, and drug discovery research.

This product is a research-grade raw material and is for scientific research use only.