Human Chorionic Gonadotropin (HCG) raw materials

Human Chorionic Gonadotropin Raw Materials (HCG)

Human Chorionic Gonadotropin (HCG) is a heterodimeric glycoprotein hormone secreted by placental syncytiotrophoblasts. It consists of two subunits, alpha and beta, and exerts its biological activity by binding to the luteinizing hormone receptor (LH/CG-R). It is a core tool molecule in reproductive endocrinology, gonadal axis function research, and assisted reproductive technology.

Main Biological Activities

• Mimics LH to activate luteinizing hormone receptor: Shares the same receptor with LH, activating the cAMP signaling pathway in Leydig cells, making it a standard tool molecule for studying LH/CG receptor signaling in the gonadal axis.
• Promotes testosterone synthesis: Stimulates Leydig cells to synthesize and secrete testosterone, suitable for research on androgen synthesis pathways, testicular function, and mechanisms related to hypogonadism.
• Supports corpus luteum function: Maintains progesterone secretion by the corpus luteum in early pregnancy and extends corpus luteum lifespan, serving as an important reference molecule for research in reproductive physiology and early pregnancy maintenance mechanisms.
• Promotes oocyte final maturation: In assisted reproduction research, it mimics the LH surge to trigger oocyte final maturation and ovulation, suitable for research on follicular development and ovulation mechanisms.
• Fetal gonadal development research: Stimulates Leydig cells to secrete testosterone during male fetal development, promoting reproductive system differentiation, and serving as a research tool in gonadal development biology.
• Tumor marker research: HCG is abnormally elevated in certain non-pregnancy-related tumors (such as choriocarcinoma, testicular tumors), making it an important reference substance for tumor biomarker and related signaling pathway research.

Product Features

• Research-grade purity, stable biological activity, high batch-to-batch consistency.
• Suitable for in vitro experiments, cell culture, animal models, and reproductive endocrine drug development research.

This product is a research-grade raw material and is for scientific research use only.